Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | YES1 | P07947 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054192 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL8806022 | 0.83 | CDK2 (0.49) | MEN1KMT2AMAPTNPSR1TXNRD1 | |
| SCHEMBL9056319 | 0.78 | KMT2A (0.46) | MEN1KMT2AALDH1A1MAPTHSP90AA1 | |
| SCHEMBL8416406 | 0.75 | RXFP1 (0.41) | MEN1KMT2AALDH1A1MAPTCYP3A4 | |
| SCHEMBL8805765 | 0.75 | TXNRD1 (0.43) | MEN1KMT2AALDH1A1MAPTTXNRD1 | |
| SCHEMBL9538744 | 0.74 | TXNRD1 (0.59) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8416383 | 0.72 | MTNR1A (0.45) | KMT2AMAPTHTR6HDAC6HDAC10 | |
| SCHEMBL8805377 | 0.72 | POLB (0.44) | MEN1KMT2AALDH1A1MAPTHSP90AA1 | |
| SCHEMBL8418190 | 0.71 | CYP19A1 (0.58) | MEN1KMT2AALDH1A1HTTCYP3A4 | |
| SCHEMBL9053943 | 0.70 | HTR6 (0.47) | MEN1KMT2AALDH1A1HTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |