Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8805765 | 0.87 | TXNRD1 (0.43) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL9054192 | 0.73 | ALDH1A1 (0.46) | CYP3A4CYP2C19MEN1KMT2APOLB | |
| SCHEMBL8816712 | 0.71 | MEN1 (0.47) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL8804608 | 0.70 | CYP1A2 (0.46) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL8805489 | 0.70 | CYP1A2 (0.45) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL8806339 | 0.69 | CYP1A2 (0.44) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL8805387 | 0.67 | MTNR1A (0.48) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL7853508 | 0.66 | MAPT (0.58) | HPGDMEN1KMT2APOLBMAPT | |
| SCHEMBL8805180 | 0.64 | KCNQ2 (0.58) | TDP1CYP1A2CYP3A4HPGDTSHR | |
| SCHEMBL8805163 | 0.63 | EGFR (0.53) | TDP1CYP1A2CYP3A4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |