Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | KDM1B | Q8NB78 | 2/20 | 0.49 |
| ▸ | RCOR1 | Q9UKL0 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 7/20 | 0.46 |
| ▸ | HTR1D | P28221 | 7/20 | 0.46 |
| ▸ | HTR1B | P28222 | 7/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | FLT3 | P36888 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306751 | 0.94 | KDM1A (0.51) | KDM1AMAOAKDM1BRCOR1ALDH1A1 | |
| SCHEMBL6309047 | 0.85 | KDM1A (0.47) | KDM1AMAOAKDM1BRCOR1ALDH1A1 | |
| SCHEMBL7809208 | 0.78 | HTR1A (0.53) | ALDH1A1TSHRGAAHTR1AHTR1D | |
| SCHEMBL6313054 | 0.77 | MAPT (0.61) | HTR1AHTR1DHTR1BNPC1TP53 | |
| SCHEMBL6309053 | 0.76 | HTR1A (0.46) | KDM1AMAOAKDM1BRCOR1ALDH1A1 | |
| SCHEMBL3949525 | 0.76 | HTR1A (0.62) | ALDH1A1GAAHTR1AHTR1DHTR1B | |
| SCHEMBL6308769 | 0.76 | NPC1 (0.60) | ALDH1A1TSHRGAAHTR1AHTR1D | |
| SCHEMBL6305476 | 0.76 | HTR1A (0.54) | HTR1AHTR1DHTR1BNPC1TP53 | |
| SCHEMBL3583048 | 0.74 | MGLL (0.72) | ALDH1A1TSHRNPC1TP53MAPT | |
| SCHEMBL6308472 | 0.74 | HTR1A (0.54) | HTR1AHTR1DHTR1BKDRHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |