Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890714 | 0.88 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL9053850 | 0.76 | LMNA (0.48) | ALDH1A1GAAMAPTNPSR1LMNA | |
| SCHEMBL9053936 | 0.75 | ALDH1A1 (0.43) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL10887977 | 0.70 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL10887982 | 0.70 | ALDH1A1 (0.50) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL9145266 | 0.69 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTNPSR1LMNA | |
| SCHEMBL10880739 | 0.67 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL10880745 | 0.67 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1GAAMAPTLMNA | |
| SCHEMBL9053887 | 0.67 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTNPSR1LMNA | |
| SCHEMBL10881709 | 0.64 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1GAAMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0508955-B1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA GEIGY AG (CH) | 1996-06-19 | — | — | EP | claimed |
| EP-0508955-A1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA-GEIGY AG (CH) | 1992-10-14 | — | — | EP | claimed |
| EP-0508955-B1 | Use of 2-iminothiazolidin-4-one derivatives as new medicaments | CIBA GEIGY AG (CH) | 1996-06-19 | — | — | EP | disclosed |
| US-5229405-A | Rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1993-07-20 | — | — | US | disclosed |