Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053850 | 0.84 | LMNA (0.48) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL10814618 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL10812313 | 0.81 | MAPK1 (0.39) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL12186945 | 0.72 | LMNA (0.49) | ALDH1A1MAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL9053874 | 0.72 | LMNA (0.49) | ALDH1A1MAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL733447 | 0.70 | MAPK1 (0.41) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL9054381 | 0.69 | ALDH1A1 (0.44) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL9054133 | 0.68 | LMNA (0.45) | ALDH1A1MAPTNPSR1KDM4EMAPK1 | |
| SCHEMBL9053887 | 0.67 | ALDH1A1 (0.39) | ALDH1A1GAAMAPTNPSR1KDM4E | |
| SCHEMBL9494274 | 0.64 | LMNA (0.52) | ALDH1A1GAAMAPTNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378719-A | Antiarthritic agents; rheumatic diseases | CIBA-GEIGY CORPORATION (US) | 1995-01-03 | — | — | US | disclosed |
| EP-0548018-A1 | Imidazoles | CIBA-GEIGY AG (CH) | 1993-06-23 | — | — | EP | disclosed |