Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD3 | P35462 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053666 | 0.93 | OPRM1 (0.43) | P2RX7OPRD1OPRM1OPRK1SETD7 | |
| SCHEMBL9054632 | 0.90 | OPRM1 (0.43) | P2RX7OPRD1OPRM1OPRK1SETD7 | |
| SCHEMBL9053981 | 0.88 | KDM4E (0.42) | P2RX7OPRD1OPRM1OPRK1SETD7 | |
| SCHEMBL9054400 | 0.82 | DRD2 (0.42) | OPRD1OPRM1OPRK1SIGMAR1HTR7 | |
| SCHEMBL9053324 | 0.75 | P2RX7 (0.55) | P2RX7OPRM1OPRK1DRD2DRD3 | |
| SCHEMBL9052502 | 0.74 | DRD2 (0.54) | P2RX7DRD2DRD3DRD4 | |
| SCHEMBL13904314 | 0.73 | SIGMAR1 (0.59) | P2RX7OPRD1OPRM1OPRK1SETD7 | |
| SCHEMBL9053843 | 0.73 | SETD7 (0.57) | OPRM1SETD7SIGMAR1HTR7DRD2 | |
| SCHEMBL9249824 | 0.73 | SETD7 (0.57) | P2RX7OPRD1OPRM1OPRK1SETD7 | |
| SCHEMBL9253379 | 0.73 | SETD7 (0.57) | P2RX7OPRD1OPRM1OPRK1SETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |