Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL905445 | 1.00 | CA2 (0.52) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL6157245 | 0.93 | GPR84 (0.54) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL1042654 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL28727416 | 0.91 | GPR84 (0.52) | CA2MAPK1ACE2GPR84FFAR1 | |
| SCHEMBL29098805 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL338004 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL338277 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL5860202 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL2928745 | 0.91 | GPR84 (0.57) | ACE2GPR84FFAR1SLC1A2SLC1A1 | |
| SCHEMBL28938780 | 0.91 | GPR84 (0.52) | CA2MAPK1ACE2GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080233621-A1 | Method For Producing Alcohol and Carboxylic Acid Having Optical Activity | API CORPORATION (JP) | 2008-09-25 | — | — | US | claimed |
| CN-1950508-A | Process for producing optically active alcohol and carboxylic acid | API CORP (JP) | 2007-04-18 | — | — | CN | claimed |
| EP-1712630-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AND CARBOXYLIC ACID | API Corporation (JP) | 2006-10-18 | — | — | EP | claimed |
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |
| US-7981645-B2 | Enzymatic asymmetric decarboxylation of disubstituted malonic acids | BIOSPRING GMBH (DE) | 2011-07-19 | — | — | US | disclosed |
| EP-2278014-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |
| EP-2270178-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20100144010-A1 | Enzymatic Asymmetric Decarboxylation of Disubstituted Malonic Acids | BIOSPRING GMBH (DE) | 2010-06-10 | — | — | US | disclosed |
| US-20080233621-A1 | Method For Producing Alcohol and Carboxylic Acid Having Optical Activity | API CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |
| CN-1950508-A | Process for producing optically active alcohol and carboxylic acid | API CORP (JP) | 2007-04-18 | — | — | CN | disclosed |
| EP-1712630-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AND CARBOXYLIC ACID | API Corporation (JP) | 2006-10-18 | — | — | EP | disclosed |
| US-7060818-B2 | Synthesis of macrocyclic tetraamido compounds and new metal insertion process | CARNEGIE MELLON UNIVERSITY (US) | 2006-06-13 | — | — | US | disclosed |
| US-6384279-B1 | OXIDIZING A DIAMIDODIOL TO FORM A DIACID FOLLOWED BY COUPLING WITH AN ARYL DIAMINE | THE CLOROX COMPANY | 2002-05-07 | — | — | US | disclosed |
| US-20020028970-A1 | SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | THE CLOROX COMPANY | 2002-03-07 | — | — | US | disclosed |
| US-6297400-B1 | CHELATING AGENTS FOR IMPROVED WASHFASTNESS OF DYE WHEN IN A BLEACHING ENVIRONMENT | THE CLOROX COMPANY | 2001-10-02 | — | — | US | disclosed |
| WO-2001002343-A1 | IMPROVED SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | THE CLOROX COMPANY (US) | 2001-01-11 | — | — | WO | disclosed |
| EP-0207599-A1 | Arachidonic acid analogues | BEECHAM GROUP PLC (GB) | 1987-01-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028970-A1 | SYNTHESIS OF A TETRAAMIDO MACROCYCLE LIGAND FROM A NOVEL DIAMIDODIOL | DDT, DDC, MLYCD | CA2 2243/4885MAPK1 1204/4885ACE2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.