Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 5/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.49 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13621464 | 0.82 | TAAR1 (0.57) | OPRK1CYP2D6CYP2C19ADRB2ADRB1 | |
| SCHEMBL1541692 | 0.82 | TAAR1 (0.57) | OPRK1CYP2D6CYP2C19ADRB2ADRB1 | |
| SCHEMBL13621571 | 0.82 | TAAR1 (0.57) | OPRK1CYP2D6CYP2C19ADRB2ADRB1 | |
| SCHEMBL6280812 | 0.80 | HIF1A (0.54) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| SCHEMBL8284239 | 0.80 | HIF1A (0.54) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| SCHEMBL16096523 | 0.80 | HIF1A (0.54) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| Hydrochloric Acid SCHEMBL4739557 | 0.78 | LMNA (0.56) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| SCHEMBL28041147 | 0.78 | ESR1 (0.52) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| SCHEMBL3870141 | 0.77 | HIF1A (0.49) | OPRK1ADRB2HIF1AADRB1HTR1A | |
| SCHEMBL4823405 | 0.75 | ALDH1A1 (0.47) | OPRK1HIF1ASLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0356035-B1 | Arylkalkyl-amines and -amides having anticonvulsant and neuroprotective properties | ASTRA AB (SE) | 1996-03-13 | — | — | EP | disclosed |