Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 5/20 | 0.48 |
| ▸ | NOS3 | P29474 | 3/20 | 0.46 |
| ▸ | NOS2 | P35228 | 2/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7086428 | 0.99 | ALDH1A1 (0.53) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL9053769 | 0.85 | LMNA (0.58) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL7080394 | 0.84 | SMN1; SMN2 (0.51) | RAB9ANPC1SMN1; SMN2KMT2ANOS1 | |
| SCHEMBL9046185 | 0.84 | NOS1 (0.58) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7082816 | 0.84 | NOS1 (0.52) | ALDH1A1MAPTGAARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7134297 | 0.84 | LMNA (0.57) | ALDH1A1MAPTGAARAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL7078869 | 0.83 | NOS3 (0.59) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7081205 | 0.82 | NOS1 (0.66) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL7077721 | 0.82 | MEN1 (0.53) | ALDH1A1MAPTGAARAB9ANPC1 | |
| SCHEMBL9055144 | 0.81 | MAPT (0.59) | ALDH1A1MAPTGAARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0713483-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | Astra Aktiebolag (SE) | 1996-05-29 | — | — | EP | claimed |
| WO-1995005363-A1 | AMIDINE DERIVATIVES WITH NITRIC OXIDE SYNTHETASE ACTIVITIES | ASTRA AKTIEBOLAG (SE) | 1995-02-23 | — | — | WO | claimed |