Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 6/20 | 0.52 |
| ▸ | HTR1D | P28221 | 4/20 | 0.52 |
| ▸ | HTR1B | P28222 | 4/20 | 0.52 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6308933 | 0.80 | SMN1; SMN2 (0.57) | HTR1AHTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL6308472 | 0.79 | HTR1A (0.54) | HTR1AHTR1DHTR1BHRH4 | |
| SCHEMBL9058908 | 0.78 | HTR1A (0.81) | HTR1AHTR1DHTR1B | |
| SCHEMBL6307023 | 0.78 | ACHE (0.55) | HTR1AHTR1DHTR1BHRH4ALDH1A1 | |
| SCHEMBL4790558 | 0.74 | CNR1 (0.50) | KDM4EALDH1A1CYP1A2CYP3A4MAPT | |
| SCHEMBL6305476 | 0.73 | HTR1A (0.54) | HTR1AHTR1DHTR1BKDM4EMAPT | |
| SCHEMBL6001695 | 0.73 | HTR1A (0.63) | HTR1AHTR1DHTR1B | |
| SCHEMBL6393026 | 0.72 | HTR1A (0.52) | HTR1AHTR1DHTR1BKDM4EALDH1A1 | |
| SCHEMBL6306841 | 0.72 | HTR1A (0.50) | HTR1AHTR1DHTR1BKDM4E | |
| SCHEMBL6313298 | 0.71 | HTR1A (0.63) | HTR1AHTR1DHTR1BHRH4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0689536-A1 | NAPHTHALENE DERIVATIVES | PFIZER INC. (US) | 1996-01-03 | — | — | EP | disclosed |