Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 11/20 | 0.63 |
| ▸ | HTR1D | P28221 | 9/20 | 0.63 |
| ▸ | HTR1B | P28222 | 9/20 | 0.63 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6313298 | 0.80 | HTR1A (0.63) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL6306922 | 0.79 | HTR5A (0.68) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL3949525 | 0.79 | HTR1A (0.62) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL8569099 | 0.79 | HTR1A (0.62) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL6002177 | 0.77 | HTR1A (0.62) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL6000211 | 0.77 | HTR1A (0.75) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL6305872 | 0.77 | HTR1A (0.59) | HTR1AHTR1DHTR1BDRD2DRD3 | |
| SCHEMBL27359418 | 0.76 | HTR1A (0.61) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL8566993 | 0.75 | HTR1A (0.73) | HTR1AHTR1DHTR1BDRD2HTR2A | |
| SCHEMBL6312894 | 0.75 | HTR1A (0.75) | HTR1AHTR1DHTR1BSLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| EP-1603395-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004080170-A2 | AMINO SUBSTITUTED BENZO(HETERO)CYCLIC DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060166984-A1 | Amino substituted benzo(hetero)cyclic derivatives | CBR3, L3MBTL3, BRS3 | HTR1A 2209/4885HTR1D 970/4885HTR1B 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.