Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CASP9 | P55211 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055513 | 0.86 | CASP3 (0.47) | ALDH1A1KDM4ETSHRSMN1; SMN2POLB | |
| SCHEMBL9057244 | 0.84 | CASP3 (0.48) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8326999 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL8326997 | 0.84 | ALDH1A1 (0.39) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL9472968 | 0.81 | POLB (0.40) | POLB | |
| SCHEMBL9055355 | 0.81 | GRIA1 (0.31) | ALDH1A1SMN1; SMN2MAPTNPC1LMNA | |
| SCHEMBL9472971 | 0.81 | POLB (0.40) | POLB | |
| SCHEMBL9056288 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT | |
| SCHEMBL9207029 | 0.72 | CES1 (0.40) | ALDH1A1HSD17B10LMNACASP3CASP1 | |
| SCHEMBL14287061 | 0.72 | KDM4E (0.44) | ALDH1A1KDM4ETSHRSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0522494-B1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1996-10-02 | — | — | EP | claimed |
| US-5223527-A | Isatineoxime derivatives and their use | NEUROSEARCH A/S (DK) | 1993-06-29 | — | — | US | claimed |
| EP-0522494-A1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-01-13 | — | — | EP | claimed |
| EP-0522494-B1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1996-10-02 | — | — | EP | disclosed |
| US-5223527-A | Isatineoxime derivatives and their use | NEUROSEARCH A/S (DK) | 1993-06-29 | — | — | US | disclosed |
| EP-0522494-A1 | Novel isatineoxime derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1993-01-13 | — | — | EP | disclosed |