Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057039 | 0.84 | MAPK8 (0.41) | MAPK8LMNAMEN1KMT2AGRM2 | |
| Hydrochloric Acid SCHEMBL9055968 | 0.82 | LMNA (0.43) | MAPK8LMNAMEN1KMT2AGRM2 | |
| SCHEMBL9055563 | 0.76 | MAPK8 (0.37) | MAPK8LMNAMEN1KMT2AGRM2 | |
| SCHEMBL9055411 | 0.76 | GAA (0.38) | MAPK8MEN1KMT2AGRM2GAA | |
| SCHEMBL9056332 | 0.75 | MAPK8 (0.44) | MAPK8MEN1KMT2ACYP2C19HTT | |
| SCHEMBL9055113 | 0.71 | MAPK8 (0.51) | MAPK8MEN1KMT2ATP53GRM2 | |
| SCHEMBL27377876 | 0.71 | TP53 (0.45) | LMNAMEN1KMT2ATP53GRM2 | |
| SCHEMBL30751303 | 0.71 | TP53 (0.45) | LMNAMEN1KMT2ATP53GRM2 | |
| SCHEMBL9055819 | 0.71 | MAPK8 (0.39) | MAPK8LMNAMEN1KMT2AGRM2 | |
| SCHEMBL10686348 | 0.71 | ALDH1A1 (0.50) | LMNAMEN1KMT2ATP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002510-A1 | NOVEL 1-[4(AMINO METHYL)PHENYL] SUBSTITUTED QUINOLONE CARBOXYLIC ACIDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-01 | — | — | WO | disclosed |