Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL9044272 | 0.75 | RORC (0.47) | LMNAMAPT | |
| SCHEMBL21864732 | 0.75 | GPR119 (0.35) | IDO1CRBNTBXAS1PDE3BPDE3A | |
| SCHEMBL255950 | 0.73 | LMNA (0.64) | MAOAMAOBNOTUMCYP19A1CYP11B1 | |
| SCHEMBL21864677 | 0.72 | CYP2D6 (0.46) | CYP19A1 | |
| Bromide SCHEMBL29232997 | 0.72 | LMNA (0.62) | MAOAMAOBNOTUMCYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL28349198 | 0.72 | LMNA (0.62) | MAOAMAOBTBXAS1NOTUMCYP19A1 | |
| SCHEMBL23900357 | 0.67 | CYP19A1 (0.50) | IDO1CRBNTBXAS1PDE3BPDE3A | |
| SCHEMBL28274864 | 0.66 | CYP11B1 (0.71) | MAOAMAOBIDO1NOTUMCYP19A1 | |
| SCHEMBL6706742 | 0.66 | MAOB (0.51) | MAOAMAOBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL23532463 | 0.65 | NOTUM (0.62) | MAOAMAOBIDO1NOTUMCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8151368-A | — | — | None | — | — | JP | disclosed |
| JP-H08151368-A | NEW NAPHTYRIDONE OR QUINOLONE COMPOUND OR THEIR SALTS AND ANTIVIRAL COMPRISING THE SAME | TOYAMA CHEM CO LTD | 1996-06-11 | — | — | JP | disclosed |