Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 3/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11695646 | 0.73 | ACHE (0.47) | ACHEDRD1PARP1MEN1KMT2A | |
| SCHEMBL26956143 | 0.72 | CHRNB2 (0.49) | ACHEDRD1HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL21980652 | 0.71 | CHRNB2 (0.48) | ACHEDRD1HTR2CHTR2B | |
| SCHEMBL29052203 | 0.69 | DRD2 (0.51) | ACHEDRD1HTR2CHTR2B | |
| SCHEMBL7855227 | 0.69 | HTR2C (0.49) | ACHEHTR2CHTR2B | |
| Bromide SCHEMBL9002886 | 0.63 | MAOA (0.33) | MEN1KMT2AGAAKDM4EALDH1A1 | |
| SCHEMBL30617258 | 0.63 | TSHR (0.46) | ACHEDRD1PARP1MAP2K3SMN1; SMN2 | |
| SCHEMBL13169714 | 0.63 | MAP2K3 (0.48) | ACHEDRD1PARP1MAP2K3MEN1 | |
| SCHEMBL12059598 | 0.62 | ACHE (1.00) | ACHEMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5585144 | 0.62 | HTR2C (0.51) | MEN1KMT2AGAAHTR1AADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996015111-A9 | METHOD AND INTERMEDIATES FOR THE SYNTHESIS OF KORUPENSAMINES | — | 1996-08-01 | — | — | WO | disclosed |
| WO-1996015111-A1 | METHOD AND INTERMEDIATES FOR THE SYNTHESIS OF KORUPENSAMINES | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-05-23 | — | — | WO | disclosed |