Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 11/20 | 0.46 |
| ▸ | ITGAV | P06756 | 11/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 10/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054703 | 0.90 | ITGB3 (0.45) | ITGB3ITGAVITGA2B | |
| SCHEMBL9055878 | 0.89 | ITGB3 (0.41) | ITGB3ITGAVITGA2BGAASMN1; SMN2 | |
| SCHEMBL9057064 | 0.82 | F2 (0.51) | ITGB3ITGAVITGA2BGAAMAPT | |
| SCHEMBL9054860 | 0.81 | ITGB3 (0.42) | ITGB3ITGAVITGA2B | |
| SCHEMBL9059149 | 0.80 | F2 (0.54) | — | |
| SCHEMBL9056463 | 0.79 | F2 (0.44) | ITGB3ITGAVITGA2BGAAMAPT | |
| SCHEMBL9056467 | 0.77 | ITGB3 (0.43) | ITGB3ITGAVITGA2BGAAMAPT | |
| SCHEMBL9055123 | 0.76 | ITGB3 (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL9056416 | 0.76 | ITGB3 (0.44) | ITGB3ITGAVITGA2B | |
| SCHEMBL9055303 | 0.74 | ITGB3 (0.44) | ITGB3ITGAVITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002517-A1 | SUBSTITUTED ARYLSULFONAMIDES, THEIR PREPARATION AND USE AS THROMBIN-INHIBITING MEDICAMENTS | DR. KARL THOMAE GMBH (DE) | 1996-02-01 | — | — | WO | disclosed |