Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.36 |
| ▸ | FEN1 | P39748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9061264 | 0.88 | MMP3 (0.40) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9062806 | 0.86 | MMP3 (0.39) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9056026 | 0.86 | MMP3 (0.39) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9061279 | 0.80 | MMP3 (0.42) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9055893 | 0.79 | MMP3 (0.43) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9055437 | 0.77 | AGTR1 (0.40) | — | |
| SCHEMBL9058030 | 0.76 | SCN9A (0.42) | MMP3 | |
| SCHEMBL9055944 | 0.76 | MMP3 (0.43) | MMP3GPR119ALOX5APFEN1 | |
| SCHEMBL9055895 | 0.76 | MMP3 (0.45) | MMP3GPR119 | |
| SCHEMBL9042695 | 0.76 | AGTR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0721454-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA. S.A. (ES) | 1996-07-17 | — | — | EP | disclosed |
| WO-1996004273-A1 | NEW PYRAZOLE DERIVATIVES AS ANGIOTENSIN II ANTAGONIST | J. URIACH & CIA, S.A. (ES) | 1996-02-15 | — | — | WO | disclosed |