SCHEMBL9056011

SCHEMBL9056011

COc1ccc(OC)c(C(=O)C(O)c2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.53
NPSR1 Q6W5P4 2/20 0.53
HTT P42858 1/20 0.53
ALDH1A1 P00352 2/20 0.51
HSD11B1 P28845 1/20 0.51
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
RAB9A P51151 1/20 0.50
POLB P06746 2/20 0.48
KDM4E B2RXH2 2/20 0.48
ABCG2 Q9UNQ0 1/20 0.47
LMNA P02545 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
TSHR P16473 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11283361 0.88 TDP1 (0.55) MAPTHTTALDH1A1KMT2AMEN1
SCHEMBL277654 0.83 HPGD (0.56) HTTALDH1A1KMT2AMEN1RAB9A
SCHEMBL28062466 0.82 LMNA (0.46) MAPTHTTALDH1A1KMT2AMEN1
Methoxymethane SCHEMBL5593577 0.81 HPGD (0.55) HTTALDH1A1KMT2AMEN1RAB9A
SCHEMBL9850361 0.81 LMNA (0.44) MAPTHTTALDH1A1KMT2AMEN1
SCHEMBL11246241 0.81 CPS1 (0.50) HTTALDH1A1LMNATDP1L3MBTL1
SCHEMBL679704 0.79 MAPT (0.49) MAPTALDH1A1KMT2AMEN1RAB9A
SCHEMBL29504856 0.79 LMNA (0.47) MAPTHTTKMT2AMEN1ABCG2
SCHEMBL13761323 0.78 MAPT (0.62) MAPTNPSR1HTTALDH1A1HSD11B1
SCHEMBL17785925 0.78 LMNA (0.46) MAPTNPSR1HTTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564282-A2 Bis-dithiobenzilnickel complexes for usae in near-infrared absorbing materials and benzoin derivatives as intermediates therefor NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-10-06 EP claimed
EP-0564282-B1 Bis-dithiobenzilnickel complexes for use in near-infrared absorbing materials and benzoin derivatives as intermediates therefor JUJO PAPER CO LTD (JP) 1996-07-03 EP disclosed
US-5484689-A SUBSTRATE WITH OPTICAL RECORDING LAYER AND COLORLESSS DYE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-01-16 US disclosed
EP-0564282-A2 Bis-dithiobenzilnickel complexes for usae in near-infrared absorbing materials and benzoin derivatives as intermediates therefor NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1993-10-06 EP disclosed