SCHEMBL277654

SCHEMBL277654

COc1ccccc1C(=O)C(O)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.56
ALDH1A1 P00352 2/20 0.56
LMNA P02545 3/20 0.52
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
KCNA3 P22001 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 1/20 0.49
CTSD P07339 1/20 0.49
HTT P42858 1/20 0.49
XBP1 P17861 1/20 0.48
MAPK1 P28482 1/20 0.47
TP53 P04637 1/20 0.46
GLA P06280 1/20 0.46
STAT3 P40763 1/20 0.46
MEN1 O00255 1/20 0.46
CRHBP P24387 1/20 0.46
KMT2A Q03164 1/20 0.46
CRHR2 Q13324 1/20 0.46
CA12 O43570 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methoxymethane SCHEMBL5593577 0.98 HPGD (0.55) HPGDALDH1A1LMNACES2CES1
Acrylic Acid SCHEMBL11117630 0.91 HPGD (0.49) HPGDALDH1A1LMNACES2CES1
SCHEMBL29384 0.87 USP2 (0.52) HPGDALDH1A1LMNACES2CES1
SCHEMBL8800967 0.87 HPGD (0.48) HPGDALDH1A1LMNACES2CES1
Bicarbonate SCHEMBL1969232 0.86 USP2 (0.51) HPGDALDH1A1LMNACES2CES1
Bicarbonate SCHEMBL31648960 0.86 USP2 (0.51) HPGDALDH1A1LMNACES2CES1
Methoxymethane SCHEMBL28122245 0.86 USP2 (0.51) HPGDALDH1A1LMNACES2CES1
Hydrochloric Acid SCHEMBL11475025 0.86 TSHR (0.50) HPGDALDH1A1LMNANPC1RAB9A
SCHEMBL27623521 0.86 KAT6A (0.49) HPGDALDH1A1LMNACES2CES1
SCHEMBL28029106 0.86 HPGD (0.47) HPGDALDH1A1LMNACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106496030-A Preparation method and applications of the cigarette with latent perfume monomer p-Methoxybenzoic acid esters 湖北中烟工业有限责任公司 2017-03-15 CN claimed
EP-3041627-A1 METAL SINTERING FILM COMPOSITIONS Henkel IP & Holding GmbH (DE) 2016-07-13 EP claimed
CN-1678325-A Sapogenin derivatives, their synthesis and use and method based upon the use PHYTOTECH LTD (GB) 2005-10-05 CN claimed
EP-0516375-B1 Thermosetting powder coating composition ROHM & HAAS (US) 1995-02-08 EP claimed
US-5266657-A Polyester, hydroxyalkylamide curing agent ROHM AND HAAS COMPANY (US) 1993-11-30 US claimed
EP-0516375-A2 Thermosetting powder coating composition ROHM AND HAAS COMPANY (US) 1992-12-02 EP claimed
EP-0067964-B1 PROCESS FOR THE PREPARATION OF 2-ISOSORBIDE NITRATE Heinrich Mack Nachf. (DE) 1985-04-03 EP claimed
US-12036206-B2 Compositions and methods for pain relief CROSS III WILLIAM H (US) 2024-07-16 US disclosed
CN-117813552-A Photosensitive composition for pattern formation and flexographic plate 日本瑞翁株式会社 2024-04-02 CN disclosed
US-20240041054-A1 ROSA CANINA ROSEHIP UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2024-02-08 US disclosed
CN-115190892-B High molecular weight acrylic triblock copolymer and adhesive composition containing the same 株式会社可乐丽 2024-01-30 CN disclosed
EP-4294361-A1 ROSEHIP UNIVERSITA' DEGLI STUDI DI CAGLIARI (IT) 2023-12-27 EP disclosed
CN-117120925-A Photosensitive laminate and method for manufacturing circuit board using the same 可隆工业株式会社 2023-11-24 CN disclosed
US-4328111-A CORROSION INHIBITION STANDARD OIL COMPANY (INDIANA) (US) 1982-05-04 US disclosed
EP-0046028-A2 Imaging process and article employing photolabile, blocked surfactant MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-17 EP disclosed
US-4224319-A AMINO ACID, TRIGLYCERIDE, VITAMINS A AND E MARCADET ERNEST 1980-09-23 US disclosed
US-4221646-A Treated polyetherurethane photopolymer composition containing triaryl phosphine THE GOODYEAR TIRE & RUBBER COMPANY (US) 1980-09-09 US disclosed
US-4116965-A STYRYL DYESTUFFS CONTAINING CERTAIN AMINO, CYANOPYRIDINE MOIETIES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4061834-A NITROMETHANE OR ACETONITRILE SOLVENT THE UNITED STATES OF AMERICA AS REPRESENTED BY THE ADMINISTRATOR OF THE NATIONAL AERONAUTICS AND SPACE ADMINISTRATION (US) 1977-12-06 US disclosed
US-3972928-A Regulating plant growth with quaternary phosphonium aliphatic carboxamide salts BAYCHEM CORPORATION (US) 1976-08-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12036206-B2 Compositions and methods for pain relief CBS, CTH, CPT1B HPGD 1833/4885ALDH1A1 1445/4885LMNA 1786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.