Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | KMO | O15229 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 3/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781859 | 0.90 | IDO1 (0.34) | ADORA1LMNAHPGDKDM4EMAPT | |
| SCHEMBL10590618 | 0.86 | KDM4E (0.36) | LMNAHPGDKDM4EMAPTALOX15 | |
| SCHEMBL9336008 | 0.85 | AHR (0.36) | ADORA1LMNAHPGDKDM4EMAPT | |
| SCHEMBL5812554 | 0.85 | CTSS (0.34) | LMNAHPGDSLC6A3 | |
| SCHEMBL10589846 | 0.83 | KDM4C (0.36) | HPGDKDM4EMAPTSLC6A2SLC6A4 | |
| SCHEMBL7500290 | 0.81 | AHR (0.37) | ADORA1LMNAHPGDKDM4EMAPT | |
| SCHEMBL8072565 | 0.81 | KIF11 (0.36) | ADORA1MAPTMAPK14 | |
| SCHEMBL9056032 | 0.80 | AHR (0.36) | ADORA1LMNAHPGDMAPTMAPK14 | |
| SCHEMBL10590186 | 0.80 | TDP1 (0.46) | HPGDKDM4EMAPTSLC6A2SLC6A4 | |
| SCHEMBL10592455 | 0.79 | ADORA1 (0.39) | ADORA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455263-A | Administering substituted arylpyrrole compounds | AMERICAN CYANAMID COMPANY (US) | 1995-10-03 | — | — | US | disclosed |
| EP-0347488-B1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID CO (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5310938-A | Miticides, insecticides, parasiticides, and anthelmintics | AMERICAN CYANAMID COMPANY (US) | 1994-05-10 | — | — | US | disclosed |
| EP-0312723-B1 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID CO (US) | 1993-12-22 | — | — | EP | disclosed |
| US-5010098-A | Arylpyrrole insecticidal acaricidal and nematicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
| US-4929634-A | ARYLPYRROLE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 1990-05-29 | — | — | US | disclosed |
| EP-0358047-A2 | Method of controlling phytopathogenic fungi | AMERICAN CYANAMID COMPANY (US) | 1990-03-14 | — | — | EP | disclosed |
| EP-0347488-A1 | Arylpyrrole insecticidal acaricidal and nematicidal agents and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-12-27 | — | — | EP | disclosed |
| EP-0312723-A2 | Method of and bait compositions for controlling mollusks | AMERICAN CYANAMID COMPANY (US) | 1989-04-26 | — | — | EP | disclosed |