Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.56 |
| ▸ | RAB9A | P51151 | 10/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 10/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | USP8 | P40818 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055922 | 0.77 | KDM4E (0.41) | SMN1; SMN2PIK3CGMAPTHPGDKDM4E | |
| SCHEMBL31171044 | 0.73 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL12749634 | 0.72 | NPC1 (1.00) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL4846271 | 0.72 | PIK3CG (0.62) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL27644919 | 0.71 | RAB9A (0.61) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL18236257 | 0.69 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL4843137 | 0.69 | PIK3CG (0.76) | NPC1RAB9ASMN1; SMN2LMNANFKB1 | |
| SCHEMBL5058200 | 0.68 | AKR1C3 (0.46) | NPC1RAB9ASMN1; SMN2MAPTHPGD | |
| SCHEMBL25916384 | 0.67 | MAPT (0.57) | NPC1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL3278505 | 0.67 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996006089-A1 | SUBSTITUTED BIPHENYL DERIVATIVES AND THEIR USE AS HERBICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1996-02-29 | — | — | WO | disclosed |