Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9055138 | 0.88 | HPGD (0.44) | LMNADRD2DRD4HPGDTSHR | |
| SCHEMBL4043208 | 0.76 | LMNA (0.70) | P2RX4LMNADRD2DRD4HPGD | |
| SCHEMBL4038858 | 0.76 | LMNA (0.54) | P2RX4LMNADRD2DRD4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL4045240 | 0.74 | LMNA (0.68) | P2RX4LMNADRD2DRD4HPGD | |
| SCHEMBL4213975 | 0.74 | LMNA (0.52) | P2RX4LMNADRD2DRD4ALDH1A1 | |
| SCHEMBL5953434 | 0.69 | DRD2 (0.47) | LMNADRD2DRD4ALDH1A1RAB9A | |
| SCHEMBL10667481 | 0.68 | HPGD (0.44) | HPGDTSHRALDH1A1GAANPC1 | |
| Hydrochloric Acid SCHEMBL9054931 | 0.68 | DRD2 (0.46) | LMNADRD2DRD4ALDH1A1RAB9A | |
| SCHEMBL5953609 | 0.67 | DRD2 (0.48) | LMNADRD2DRD4ALDH1A1TP53 | |
| SCHEMBL6693464 | 0.66 | LMNA (0.47) | LMNADRD2DRD4HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0726265-A1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | CIBA-GEIGY AG (CH) | 1996-08-14 | — | — | EP | claimed |
| EP-0726265-A1 | 10-Aminoaliphatyl-dibenz(b,f)oxepins with antineurodegenarative activity | CIBA-GEIGY AG (CH) | 1996-08-14 | — | — | EP | disclosed |