Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CTSV | O60911 | 3/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PPIA | P62937 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8321520 | 0.86 | CCR5 (0.46) | ALDH1A1 | |
| SCHEMBL8317985 | 0.85 | HTR1A (0.46) | — | |
| SCHEMBL8678003 | 0.82 | MEN1 (0.45) | MEN1KMT2AMAPTCYP19A1ITGA4 | |
| SCHEMBL8678006 | 0.79 | MEN1 (0.43) | MEN1KMT2AMAPTCYP19A1ITGA4 | |
| SCHEMBL8676554 | 0.78 | MEN1 (0.45) | MEN1KMT2AMAPTCYP19A1ITGA4 | |
| SCHEMBL8323207 | 0.74 | MEN1 (0.44) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL8321876 | 0.74 | CYP19A1 (0.44) | MEN1KMT2AMAPTCYP19A1ALDH1A1 | |
| SCHEMBL8324470 | 0.73 | PTGER1 (0.48) | ALDH1A1 | |
| SCHEMBL22117685 | 0.72 | MEN1 (0.60) | MEN1KMT2AMAPTCYP19A1ITGA4 | |
| SCHEMBL31071630 | 0.72 | MEN1 (0.60) | MEN1KMT2AMAPTCYP19A1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996011902-A1 | PHARMACEUTICALLY ACTIVE SUBSTITUTED AROMATIC COMPOUNDS | ZENECA LIMITED (GB) | 1996-04-25 | — | — | WO | disclosed |