Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | UBE2M | P61081 | 5/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8817855 | 0.91 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1POLBALOX15 | |
| SCHEMBL9056629 | 0.89 | KMT2A (0.38) | KMT2AMEN1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL8856166 | 0.84 | TP53 (0.37) | UBE2MDCUN1D1ALDH1A1ALOX15TSHR | |
| SCHEMBL8808662 | 0.83 | KMT2A (0.38) | KMT2AMEN1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL8856113 | 0.82 | UBE2M (0.40) | KMT2AUBE2MDCUN1D1ALDH1A1LMNA | |
| SCHEMBL8807965 | 0.82 | GAA (0.47) | KMT2AMEN1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL8810238 | 0.81 | KMT2A (0.41) | KMT2AMEN1UBE2MDCUN1D1ALDH1A1 | |
| SCHEMBL8808860 | 0.80 | USP2 (0.43) | KMT2AUBE2MDCUN1D1ALDH1A1USP2 | |
| SCHEMBL8809049 | 0.80 | TP53 (0.42) | KMT2AMEN1ALDH1A1USP2POLB | |
| SCHEMBL8807728 | 0.80 | TP53 (0.42) | KMT2AMEN1ALDH1A1USP2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |