Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | PPM1D | O15297 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.48 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | KDM1A | O60341 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21088517 | 0.89 | PPM1D (0.57) | POLBTAAR1ALDH1A1HDAC1PPM1D | |
| SCHEMBL8807024 | 0.87 | HDAC1 (0.67) | POLBTAAR1ALDH1A1HDAC1KMT2A | |
| SCHEMBL30444177 | 0.84 | KDM1A (0.54) | PPM1DEPHX1KDM1AMAOAMAOB | |
| SCHEMBL11509945 | 0.80 | ALDH1A1 (0.68) | POLBALDH1A1HDAC1CXCR4 | |
| SCHEMBL9252404 | 0.80 | ALDH1A1 (0.68) | POLBALDH1A1HDAC1CXCR4 | |
| SCHEMBL6911153 | 0.80 | ALDH1A1 (0.51) | POLBALDH1A1KMT2AEPHX1LMNA | |
| Acetic Acid SCHEMBL8071956 | 0.79 | EPHX1 (0.60) | POLBTAAR1ALDH1A1HDAC1KMT2A | |
| SCHEMBL24574127 | 0.78 | HRH3 (0.71) | POLBTAAR1ALDH1A1HDAC1KMT2A | |
| SCHEMBL1847296 | 0.78 | HRH3 (0.71) | POLBTAAR1ALDH1A1HDAC1KMT2A | |
| SCHEMBL10789534 | 0.78 | HRH3 (0.71) | POLBTAAR1ALDH1A1HDAC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |