Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 14/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 14/20 | 0.48 |
| ▸ | F2R | P25116 | 2/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.32 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.31 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.31 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056746 | 0.74 | ITGB3 (0.42) | ITGB3ITGA2BF2RCCR2 | |
| SCHEMBL13039757 | 0.69 | ITGB3 (0.71) | ITGB3ITGA2BF2RTPSAB1TPSD1 | |
| SCHEMBL29015390 | 0.67 | FOLH1 (0.51) | CCR2 | |
| SCHEMBL29015392 | 0.67 | FOLH1 (0.51) | CCR2 | |
| SCHEMBL3649385 | 0.67 | TSHR (0.45) | ITGB3ITGA2BCCR2 | |
| SCHEMBL7277043 | 0.67 | TSHR (0.45) | ITGB3ITGA2BCCR2 | |
| SCHEMBL1648380 | 0.66 | — | — | |
| SCHEMBL30140781 | 0.65 | L3MBTL1 (0.35) | — | |
| SCHEMBL29015376 | 0.64 | AGER (0.37) | CCR2 | |
| SCHEMBL7351109 | 0.63 | L3MBTL1 (0.40) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996018605-A1 | ACYLOXYISOPROPYL CARBAMATES AS PRODRUGS FOR AMINE DRUGS | MERCK & CO., INC. (US) | 1996-06-20 | — | — | WO | disclosed |