Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 4/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.36 |
| ▸ | DPP4 | P27487 | 2/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443845 | 0.89 | GABRA1 (0.35) | PNMTTAAR1 | |
| SCHEMBL4590254 | 0.80 | GABRA1 (0.44) | TAAR1 | |
| SCHEMBL20316645 | 0.79 | PNMT (0.52) | PNMTTAAR1DPP4LOXL2 | |
| SCHEMBL8074849 | 0.78 | PNMT (0.40) | PNMTTAAR1DPP4 | |
| SCHEMBL467666 | 0.78 | CYP3A4 (0.37) | PNMTTAAR1 | |
| SCHEMBL11858483 | 0.76 | TAAR1 (0.40) | TAAR1 | |
| SCHEMBL10800343 | 0.75 | TLR8 (0.40) | PNMT | |
| SCHEMBL29070930 | 0.74 | TLR8 (0.46) | — | |
| SCHEMBL5399463 | 0.73 | PNMT (0.52) | PNMTTAAR1DPP4LOXL2 | |
| SCHEMBL5497771 | 0.73 | PNMT (0.48) | PNMTTAAR1DPP4LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996014846-A1 | DIHYDROPYRIMIDINES AND USES THEREOF | SYNAPTIC PHARMACEUTICAL CORPORATION (US) | 1996-05-23 | — | — | WO | disclosed |