Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | CD44 | P16070 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PNMT | P11086 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11873762 | 0.84 | MEN1 (0.39) | CYP3A4TSHR | |
| SCHEMBL11443845 | 0.84 | GABRA1 (0.35) | TSHRHSD17B10TAAR1PNMTSLC6A2 | |
| SCHEMBL11026037 | 0.80 | CD44 (0.39) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| SCHEMBL9304737 | 0.79 | ALOX15 (0.43) | CYP3A4TSHRALDH1A1TDP1TAAR1 | |
| SCHEMBL9057723 | 0.78 | PNMT (0.45) | TAAR1PNMT | |
| SCHEMBL411734 | 0.78 | NOS2 (0.37) | CYP3A4TSHRPIK3CAALDH1A1TDP1 | |
| SCHEMBL30380395 | 0.77 | TAAR1 (0.37) | TAAR1PNMT | |
| SCHEMBL5133372 | 0.76 | CYP3A4 (0.32) | CYP3A4TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL4590254 | 0.76 | GABRA1 (0.44) | CYP3A4ALDH1A1TDP1TAAR1 | |
| SCHEMBL11858483 | 0.76 | TAAR1 (0.40) | CYP3A4TSHRALDH1A1TDP1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020167811-A1 | A CROSS-LINKING APPROACH TO MAP SMALL MOLECULE-RNA BINDING SITES IN CELLS | THE SCRIPPS RESEARCH INSTITUTE (US) | 2020-08-20 | — | — | WO | disclosed |
| EP-2387395-A1 | AXL INHIBITORS FOR USE IN COMBINATION THERAPY FOR PREVENTING, TREATING OR MANAGING METASTATIC CANCER | Rigel Pharmaceuticals, Inc. (US) | 2011-11-23 | — | — | EP | disclosed |
| US-8040491-B2 | Exposure method, substrate stage, exposure apparatus, and device manufacturing method | NIKON CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| WO-2010083465-A1 | AXL INHIBITORS FOR USE IN COMBINATION THERAPY FOR PREVENTING, TREATING OR MANAGING METASTATIC CANCER | RIGEL PHARMACEUTICALS, INC. (US) | 2010-07-22 | — | — | WO | disclosed |
| EP-1807077-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047277-A2 | INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2006-05-04 | — | — | WO | disclosed |
| US-20060019936-A1 | Methods and compositions for treating cancer | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2006-01-26 | — | — | US | disclosed |
| US-4172081-A | Benzotriazole ultraviolet stabilizers | EASTMAN KODAK COMPANY (US) | 1979-10-23 | — | — | US | disclosed |
| US-4116929-A | POLYESTERS | EASTMAN KODAK COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
| US-4017508-A | POLYMERS | EASTMAN KODAK COMPANY (US) | 1977-04-12 | — | — | US | disclosed |
| US-3997519-A | Method of producing quaternary pyridinium compounds | GAF CORPORATION (US) | 1976-12-14 | — | — | US | disclosed |