Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 3/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11443845 | 0.91 | GABRA1 (0.35) | GABRA1GABRB2TAAR1 | |
| SCHEMBL9057723 | 0.80 | PNMT (0.45) | TAAR1 | |
| SCHEMBL8090798 | 0.79 | GABRA1 (0.46) | GABRA1GABRB2HTR1ATAAR1SCN5A | |
| SCHEMBL607739 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2HTR1ATAAR1SCN5A | |
| SCHEMBL9839857 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2HTR1ATAAR1SCN5A | |
| SCHEMBL597268 | 0.78 | GABRA1 (0.50) | GABRA1GABRB2HTR1ATAAR1SCN5A | |
| SCHEMBL11858483 | 0.77 | TAAR1 (0.40) | TAAR1TP53ALDH1A1CYP3A4TDP1 | |
| SCHEMBL18378254 | 0.76 | GABRA1 (0.48) | GABRA1GABRB2HTR1ATAAR1SCN5A | |
| SCHEMBL467666 | 0.76 | CYP3A4 (0.37) | TAAR1ALDH1A1CYP3A4TDP1 | |
| SCHEMBL245773 | 0.75 | GABRA1 (0.57) | GABRA1GABRB2HTR1ATAAR1SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051419-B2 | Polymer | HALL RICHARD H (US) | 2015-06-09 | — | — | US | disclosed |
| US-20080171814-A1 | Polymer | HALL RICHARD H | 2008-07-17 | — | — | US | disclosed |