SCHEMBL9058094

SCHEMBL9058094

C=CCNCCCNC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.41
RAB9A P51151 2/20 0.38
TSHR P16473 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
MAPT P10636 1/20 0.37
PAOX Q6QHF9 1/20 0.35
FAAH O00519 1/20 0.35
ALDH1A1 P00352 3/20 0.35
GAA P10253 2/20 0.35
LMNA P02545 1/20 0.34
KMT2A Q03164 3/20 0.33
NPC1 O15118 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
MAPK1 P28482 1/20 0.33
HIF1A Q16665 1/20 0.33
MEN1 O00255 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18579931 0.89 SMN1; SMN2 (0.35) KDM4ERAB9ATSHRSMN1; SMN2MAPT
SCHEMBL632876 0.82 KDM4E (0.46) KDM4EPAOXALDH1A1KMT2AZDHHC20
SCHEMBL8530629 0.82 FAAH (0.39) KDM4ERAB9ATSHRSMN1; SMN2MAPT
SCHEMBL8032280 0.81 TSHR (0.42) KDM4ERAB9ATSHRSMN1; SMN2MAPT
SCHEMBL16309325 0.80 KDM4E (0.44) KDM4EPAOXALDH1A1KMT2AMAPK1
SCHEMBL18133016 0.79 ALDH1A1 (0.40) KDM4ERAB9ATSHRSMN1; SMN2MAPT
SCHEMBL18133015 0.79 KDM4E (0.40) KDM4EPAOXKMT2AMAPK1HIF1A
SCHEMBL112008 0.79 CYP2C19 (0.46) KDM4ETSHRPAOXKMT2AMAPK1
SCHEMBL30604 0.78
SCHEMBL20346383 0.78 KDM4E (0.38) KDM4ETSHRPAOXZDHHC20ZDHHC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3954753-B1 POLYMERIC SURFACTANTS FOR IMPROVED EMULSION AND FLOW PROPERTIES OF OILS AT LOW TEMPERATURES AFTON CHEMICAL CORP (US) 2024-06-26 EP disclosed
EP-4368689-A1 POLYMERIC SURFACTANTS FOR IMPROVED EMULSION AND FLOW PROPERTIES AT LOW TEMPERATURES Afton Chemical Corporation (US) 2024-05-15 EP disclosed
US-11584898-B2 Polymeric surfactants for improved emulsion and flow properties at low temperatures AFTON CHEMICAL CORPORATION (US) 2023-02-21 US disclosed
CN-107540565-B Preparation of N, N- (di) alkylaminoalkyl (meth) acrylamides or the corresponding esters and quaternary ammonium salts thereof 赢创运营有限公司 2022-10-21 CN disclosed
US-20220049180-A1 Polymeric Surfactants for Improved Emulsion and Flow Properties at Low Temperatures AFTON CHEMICAL CORPORATION 2022-02-17 US disclosed
EP-3954753-A1 POLYMERIC SURFACTANTS FOR IMPROVED EMULSION AND FLOW PROPERTIES AT LOW TEMPERATURES Afton Chemical Corporation (US) 2022-02-16 EP disclosed
US-10718960-B2 Method for producing contact lenses with wearing comfort ALCON INC. (CH) 2020-07-21 US disclosed
US-10556975-B2 Aqueous polymerization of thermoresponsive flocculants PHILLIPS 66 COMPANY (US) 2020-02-11 US disclosed
EP-3532276-A1 METHOD FOR PRODUCING SURFACE COATED CONTACT LENSES WITH WEARING COMFORT Novartis AG (CH) 2019-09-04 EP disclosed
EP-3344447-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON Novartis AG (CH) 2018-07-11 EP disclosed
US-20180120590-A1 METHOD FOR PRODUCING CONTACT LENSES WITH WEARING COMFORT ALCON INC. (CH) 2018-05-03 US disclosed
US-20180072825-A1 AQUEOUS POLYMERIZATION OF THERMORESPONSIVE FLOCCULANTS PHILLIPS 66 COMPANY (US) 2018-03-15 US disclosed
US-9810812-B2 Method for producing contact lenses with durable lubricious coatings thereon NOVARTIS AG (CH) 2017-11-07 US disclosed
US-20170068019-A1 METHOD FOR PRODUCING CONTACT LENSES WITH DURABLE LUBRICIOUS COATINGS THEREON ALCON INC. (CH) 2017-03-09 US disclosed
WO-1996008255-A1 TRANSDERMAL DEVICE FOR DELIVERY OF LEVONORGESTREL MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-03-21 WO disclosed