Cyclohexylamine

Cyclohexylamine

SCHEMBL9058337

NC1CCCCC1.O=C=C(c1ccccc1)c1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.38
RAB9A P51151 3/20 0.37
NPC1 O15118 2/20 0.37
KMO O15229 1/20 0.37
POLB P06746 2/20 0.36
ELANE P08246 1/20 0.36
SMYD3 Q9H7B4 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM1 P11229 1/20 0.36
CHRM3 P20309 1/20 0.36
KDM4E B2RXH2 2/20 0.36
ALDH1A1 P00352 2/20 0.36
HPGD P15428 2/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoic Acid SCHEMBL597061 0.79 TSHR (0.56) MCL1RAB9ANPC1KMOPOLB
Benzophenone SCHEMBL11575706 0.79 ALDH1A1 (0.56) MCL1RAB9ANPC1KMOPOLB
SCHEMBL80355 0.78 CES1 (0.48) POLBKDM4EALDH1A1HPGDSMN1; SMN2
Benzoic Acid SCHEMBL28845890 0.76 DAO (0.52) MCL1RAB9ANPC1KMOPOLB
SCHEMBL28632577 0.76 CES1 (0.46) POLBKDM4EALDH1A1HPGDSMN1; SMN2
Benzoic Acid SCHEMBL975786 0.75 TSHR (0.50) MCL1RAB9ANPC1KMOPOLB
Acetophenone SCHEMBL27639957 0.74 SMYD3 (0.47) MCL1RAB9ANPC1SMYD3ALDH1A1
Cyclohexylamine SCHEMBL8940507 0.74 LMNA (0.44) MCL1RAB9ANPC1POLBELANE
Isophthalic Acid SCHEMBL27861769 0.73 KMO (0.62) RAB9ANPC1KMOPOLBSMYD3
Cyclohexylamine SCHEMBL9304097 0.72 CA12 (0.50) POLBCHRM2CHRM1CHRM3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996004254-A2 BENZODIAZEPINE DERIVATIVES FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1996-02-15 WO disclosed
EP-0055917-B1 NEW BENZOTHIAZINE DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND USE THEREOF FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1984-11-21 EP disclosed
US-4399277-A 7-Amino-3-phosphonocephalosporanic acid compounds FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1983-08-16 US disclosed