SCHEMBL9058554

SCHEMBL9058554

FC1(F)Oc2cc(C(Cl)(Cl)Cl)ccc2OC1(F)Cl

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
KIF11 P52732 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11001363 0.75 MAPT (0.47) TSHRKIF11
SCHEMBL6442271 0.73 LMNA (0.32)
SCHEMBL2662892 0.71 ALDH1A1 (0.38) TSHRKIF11
SCHEMBL7702962 0.70 CTNNB1 (0.42) TSHRKIF11
SCHEMBL9077546 0.70 ALPL (0.32)
Hydrochloric Acid SCHEMBL9687836 0.68 ALPL (0.31)
SCHEMBL11114110 0.68 P2RY6 (0.33)
SCHEMBL10256454 0.66 TSHR (0.34) TSHRKIF11
SCHEMBL14446464 0.66 CNR2 (0.40) TSHRKIF11
SCHEMBL12996013 0.66 TSHR (0.34) TSHRKIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996022280-A1 N-SUBSTITUTED 1-ACYLAMINOALKYL PIPERIDINES FOR TREATMENT OF CEREBRAL DISORDERS AND DEPRESSIONS BAYER AKTIENGESELLSCHAFT (DE) 1996-07-25 WO disclosed