Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.42 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4262386 | 0.81 | PTGS2 (0.52) | ERN1ALDH1A1ACHEPTPRCS100A4 | |
| SCHEMBL1858387 | 0.76 | ALDH1A1 (0.62) | ERN1TSHRALDH1A1TDP1ACHE | |
| SCHEMBL2365111 | 0.76 | TSHR (0.48) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL9058591 | 0.75 | TSHR (0.47) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL9058049 | 0.75 | ERN1 (0.39) | ERN1TSHRALDH1A1TDP1ACHE | |
| SCHEMBL630056 | 0.74 | ALDH1A1 (0.54) | TSHRALDH1A1TDP1SMN1; SMN2HTT | |
| SCHEMBL2652355 | 0.74 | ERN1 (0.69) | ERN1TSHRALDH1A1TDP1HSD17B10 | |
| SCHEMBL5593051 | 0.73 | ERN1 (0.62) | ERN1TSHRALDH1A1TDP1ACHE | |
| SCHEMBL12798324 | 0.72 | ERN1 (0.67) | ERN1TSHRALDH1A1TDP1ACHE | |
| SCHEMBL31098731 | 0.72 | ERN1 (0.67) | ERN1TSHRALDH1A1TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |