Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6625941 | 0.79 | KMT2A (0.46) | ALDH1A1NPC1RAB9ATSHRHSD17B10 | |
| SCHEMBL16697416 | 0.77 | ALDH1A1 (0.54) | ERN1ALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL28624505 | 0.77 | NPSR1 (0.51) | ERN1ALDH1A1TSHRNPSR1LMNA | |
| SCHEMBL27934066 | 0.75 | NPSR1 (0.42) | ERN1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL9058593 | 0.75 | ERN1 (0.49) | ERN1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL27683236 | 0.74 | ERN1 (0.39) | ERN1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL31018721 | 0.74 | ALDH1A1 (0.52) | ERN1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL6553025 | 0.74 | ALDH1A1 (0.52) | ERN1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL28543486 | 0.74 | CASP1 (0.44) | ALDH1A1NPC1RAB9ATSHRCASP1 | |
| SCHEMBL27770215 | 0.74 | LOXL2 (0.45) | ERN1ALDH1A1TSHRCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |