Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PTPRC | P08575 | 3/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP4 | P49662 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7432122 | 0.83 | PTPRC (0.47) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL11379484 | 0.81 | PTGS2 (0.52) | ALDH1A1TDP1ACHEPTPRCS100A4 | |
| SCHEMBL5712945 | 0.76 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL2365111 | 0.76 | TSHR (0.48) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL9058593 | 0.75 | ERN1 (0.49) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL9058047 | 0.75 | ALDH1A1 (0.38) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL630056 | 0.74 | ALDH1A1 (0.54) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL5962192 | 0.74 | VCAM1 (0.52) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL27638357 | 0.73 | ALDH1A1 (0.62) | TSHRALDH1A1TDP1ACHEHSD17B10 | |
| SCHEMBL1800029 | 0.71 | GPR35 (0.55) | TSHRALDH1A1TDP1ACHEHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |