Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 5/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | TNF | P01375 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 3/20 | 0.46 |
| ▸ | CA2 | P00918 | 3/20 | 0.46 |
| ▸ | PTPRC | P08575 | 1/20 | 0.44 |
| ▸ | S100A4 | P26447 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31538157 | 0.82 | CA12 (0.52) | CA12CA9TNFALOX5CA4 | |
| SCHEMBL13495397 | 0.75 | PTPRC (0.53) | CA12CA9TNFALOX5CA1 | |
| SCHEMBL14876485 | 0.73 | ALOX5 (0.56) | TNFALOX5KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL14598270 | 0.73 | ALDH1A1 (0.51) | CA12CA9CA1KDM4EALDH1A1 | |
| SCHEMBL3202418 | 0.73 | PTPRC (0.58) | CA12CA9ALOX5CA4CA1 | |
| SCHEMBL30781599 | 0.73 | PTPRC (0.58) | CA12CA9ALOX5CA4CA1 | |
| SCHEMBL18017059 | 0.73 | PTPRC (0.50) | CA12CA9ALOX5CA1CA2 | |
| SCHEMBL28639253 | 0.72 | ALOX5 (0.62) | CA12CA9ALOX5CA4CA1 | |
| SCHEMBL4234480 | 0.71 | LPAR3 (0.69) | CA12CA9ALOX5CA1CA2 | |
| Potassium SCHEMBL30889113 | 0.71 | PTPRC (0.56) | CA12CA9ALOX5CA4CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016333-A1 | METHODS FOR SYNTHESIZING DIVERSE COLLECTIONS OF β-LACTAM COMPOUNDS | AFFYMAX TECHNOLOGIES, N.V. (AN) | 1996-05-30 | — | — | WO | disclosed |