Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4900404 | 0.87 | ALDH1A1 (0.56) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4253302 | 0.84 | ALDH1A1 (0.67) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4253299 | 0.84 | ALDH1A1 (0.67) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7664429 | 0.81 | ALDH1A1 (0.58) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL7664431 | 0.81 | ALDH1A1 (0.58) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4253696 | 0.80 | ALDH1A1 (0.60) | ALDH1A1G6PC1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL4253702 | 0.80 | ALDH1A1 (0.60) | ALDH1A1G6PC1SMN1; SMN2NPC1KDM4E | |
| SCHEMBL11558089 | 0.79 | CA2 (0.49) | ALDH1A1G6PC1KDM4ELMNAL3MBTL1 | |
| SCHEMBL673967 | 0.79 | CA2 (0.49) | ALDH1A1G6PC1KDM4ELMNAL3MBTL1 | |
| SCHEMBL7119990 | 0.79 | ALDH1A1 (0.55) | ALDH1A1G6PC1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020936-A1 | NOVEL THIAZOLIDIN-4-ONE DERIVATIVES | SUNKYONG INDUSTRIES CO., LTD. (KR) | 1996-07-11 | — | — | WO | disclosed |
| US-5106860-A | Treating inflammation, circulatory disease, gastrointestinal ulceration, allergies | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-04-21 | — | — | US | disclosed |
| US-5021435-A | Administering to a patient suffering from an ulcer caused by stress or gastric acid | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-06-04 | — | — | US | disclosed |
| US-4992455-A | Cardiovascular disorders | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1991-02-12 | — | — | US | disclosed |
| EP-0325496-A1 | 2-Pyridyl thiazolidin-4-one derivatives as anti-ulcer agents | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1989-07-26 | — | — | EP | disclosed |
| EP-0292305-A1 | Novel thiazolidin-4-one derivatives and acid addition salts thereof | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1988-11-23 | — | — | EP | disclosed |