Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 3/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059691 | 0.89 | KCNH2 (0.46) | — | |
| SCHEMBL27532209 | 0.87 | ALOX5 (0.44) | FFAR4 | |
| SCHEMBL8707063 | 0.87 | ALOX5 (0.44) | FFAR4 | |
| SCHEMBL9060909 | 0.79 | ALOX5 (0.49) | PARP10 | |
| SCHEMBL8706620 | 0.79 | ALOX5 (0.43) | PARP10PPARG | |
| SCHEMBL27469135 | 0.79 | ALOX5 (0.43) | PARP10PPARG | |
| SCHEMBL993764 | 0.79 | ALOX5 (0.55) | PARP10 | |
| SCHEMBL9060091 | 0.78 | MAOB (0.46) | PARP10FFAR1 | |
| SCHEMBL7969849 | 0.68 | LMNA (0.40) | — | |
| SCHEMBL9059926 | 0.67 | NCOA1 (0.45) | HRH3FFAR1FFAR4HDAC6HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996016054-A1 | CYCLOALKENYL-N-HYDROXYUREAS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-30 | — | — | WO | claimed |
| WO-1996016054-A1 | CYCLOALKENYL-N-HYDROXYUREAS | PFIZER PHARMACEUTICALS INC. (JP) | 1996-05-30 | — | — | WO | disclosed |