Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8707063 | 0.91 | ALOX5 (0.44) | ALOX5KCNH2 | |
| SCHEMBL27532209 | 0.91 | ALOX5 (0.44) | ALOX5KCNH2 | |
| SCHEMBL8706620 | 0.89 | ALOX5 (0.43) | ALOX5PARP14PARP10 | |
| SCHEMBL27469135 | 0.89 | ALOX5 (0.43) | ALOX5PARP14PARP10 | |
| SCHEMBL9407414 | 0.87 | ALOX5 (0.58) | ALOX5MAPTMEN1ALDH1A1TP53 | |
| Hydroxyurea SCHEMBL8712235 | 0.87 | ALOX5 (0.41) | ALOX5KCNH2 | |
| SCHEMBL9060091 | 0.83 | MAOB (0.46) | PARP10KCNH2SCN3A | |
| SCHEMBL9080926 | 0.80 | ALOX5 (0.36) | ALOX5 | |
| SCHEMBL9059477 | 0.79 | PPARD (0.40) | PARP10 | |
| SCHEMBL8706885 | 0.78 | CCNT1 (0.40) | ALOX5BTKPARP14PARP10SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4125820-A1 | PHARMACEUTICAL CARRIERS CAPABLE OF PH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME | PLx Opco Inc. (US) | 2023-02-08 | — | — | EP | claimed |
| CN-115666523-A | Drug carriers capable of pH dependent reconstitution and methods of making and using the same | PLX 奥普科有限公司 | 2023-01-31 | — | — | CN | claimed |
| US-20220168321-A1 | PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME | PLX OPCO INC. (US) | 2022-06-02 | — | — | US | claimed |
| US-20220000886-A1 | PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME | PLX OPCO INC. (US) | 2022-01-06 | — | — | US | claimed |
| US-10786444-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | PLX OPCO INC. (US) | 2020-09-29 | — | — | US | claimed |
| US-20200222309-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | PLX OPCO INC. (US) | 2020-07-16 | — | — | US | claimed |
| US-10646431-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | PLX OPCO INC. (US) | 2020-05-12 | — | — | US | claimed |
| US-20190070099-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | PLX OPCO INC. (US) | 2019-03-07 | — | — | US | claimed |
| US-10179104-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | PLX OPCO INC. (US) | 2019-01-15 | — | — | US | claimed |
| US-20170304190-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | PLX OPCO INC. (US) | 2017-10-26 | — | — | US | claimed |
| US-20060204577-A1 | Pharmaceutical Compositions of Drugs and Neutralized Acidic Polymers | PFIZER PRODUCTS INC. | 2006-09-14 | — | — | US | claimed |
| EP-1404300-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | Pfizer Products Inc. (US) | 2004-04-07 | — | — | EP | claimed |
| WO-2003000235-A9 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PROD INC (US) | 2003-12-24 | — | — | WO | claimed |
| US-20030091643-A1 | Amorphous mixture of acid sensitive drug and addition polymer; chemical resistance, stability | BEND RESEARCH, INC. | 2003-05-15 | — | — | US | claimed |
| US-20030054038-A1 | Pharmaceutical compositions of drugs and neutralized acidic polymers | BEND RESEARCH, INC. | 2003-03-20 | — | — | US | claimed |
| WO-2003000235-A1 | PHARMACEUTICAL COMPOSITIONS OF DISPERSIONS OF DRUGS AND NEUTRAL POLYMERS | PFIZER PRODUCTS INC. (US) | 2003-01-03 | — | — | WO | claimed |
| CN-1077568-C | Phenoxyphenyl cyclopentenyl hydroxyureas | PFIZER (US) | 2002-01-09 | — | — | CN | claimed |
| EP-0720598-B1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER (US) | 1998-10-07 | — | — | EP | claimed |
| EP-0720598-A1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER INC. (US) | 1996-07-10 | — | — | EP | claimed |
| WO-1995005360-A1 | PHENOXYPHENYL CYCLOPENTENYL HYDROXYUREAS | PFIZER INC. (US) | 1995-02-23 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10646431-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3629/4885MEN1 3423/4885 |
| US-20220000886-A1 | PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME | ABCB11, SLC47A1, SLC46A1 | ALOX5 2692/4885MAPT 2472/4885MEN1 1138/4885 |
| US-20200222309-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3385/4885MEN1 3673/4885 |
| US-20030054038-A1 | Pharmaceutical compositions of drugs and neutralized acidic polymers | PDE7A, CA6, PDE9A | ALOX5 1733/4885MAPT 543/4885MEN1 1485/4885 |
| US-20170304190-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3385/4885MEN1 3673/4885 |
| US-20030091643-A1 | Amorphous mixture of acid sensitive drug and addition polymer; chemical resistance, stability | ABCC1, ABCG2, PGD | ALOX5 387/4885MAPT 103/4885MEN1 4307/4885 |
| US-10179104-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3385/4885MEN1 3673/4885 |
| US-20220168321-A1 | PHARMACEUTICAL CARRIERS CAPABLE OF pH DEPENDENT RECONSTITUTION AND METHODS FOR MAKING AND USING SAME | ABCB11, SLC47A1, SLC46A1 | ALOX5 2692/4885MAPT 2472/4885MEN1 1138/4885 |
| US-20060204577-A1 | Pharmaceutical Compositions of Drugs and Neutralized Acidic Polymers | PDE7A, CA6, PDE9A | ALOX5 1733/4885MAPT 543/4885MEN1 1485/4885 |
| US-20190070099-A1 | pH DEPENDENT CARRIERS FOR TARGETED RELEASE OF PHARMACEUTICALS ALONG THE GASTROINTESTINAL TRACT, COMPOSITIONS THEREFROM, AND MAKING AND USING SAME | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3629/4885MEN1 3423/4885 |
| US-10786444-B2 | PH dependent carriers for targeted release of pharmaceuticals along the gastrointestinal tract, compositions therefrom, and making and using same | FFAR2, FFAR1, FFAR3 | ALOX5 57/4885MAPT 3385/4885MEN1 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.