Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9060925 | 0.88 | ALDH1A1 (0.38) | MAPTNPSR1L3MBTL1ATMKMT2A | |
| SCHEMBL9059356 | 0.87 | AKR1C3 (0.46) | MAPTNPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL9059338 | 0.78 | ALDH1A1 (0.42) | MAPTL3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL9059449 | 0.71 | SMN1; SMN2 (0.45) | L3MBTL1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL9060475 | 0.70 | ALDH1A1 (0.38) | MAPTL3MBTL1LMNAALDH1A1RAB9A | |
| SCHEMBL9059608 | 0.69 | CYP2A13 (0.52) | KMT2AMEN1ALOX15RAB9ASMN1; SMN2 | |
| SCHEMBL6531047 | 0.69 | GAA (0.46) | MAPTNPSR1L3MBTL1ATMKMT2A | |
| SCHEMBL9065218 | 0.66 | LMNA (0.68) | MAPTNPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL30228454 | 0.66 | LMNA (0.68) | MAPTNPSR1L3MBTL1KMT2AMEN1 | |
| SCHEMBL8894088 | 0.66 | LMNA (0.68) | MAPTNPSR1L3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |