Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | HTR3A | P46098 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059530 | 0.88 | MAPT (0.50) | ALDH1A1MAPTL3MBTL1NPSR1LMNA | |
| SCHEMBL9059356 | 0.86 | AKR1C3 (0.46) | ALDH1A1MAPTL3MBTL1NPSR1LMNA | |
| SCHEMBL9059338 | 0.77 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1KMT2AMEN1 | |
| SCHEMBL9059449 | 0.70 | SMN1; SMN2 (0.45) | ALDH1A1L3MBTL1LMNAKMT2AMEN1 | |
| SCHEMBL9060475 | 0.69 | ALDH1A1 (0.38) | ALDH1A1MAPTL3MBTL1LMNAKDM4E | |
| SCHEMBL3436360 | 0.69 | ADRB1 (0.60) | ALDH1A1LMNAKMT2AATMTSHR | |
| SCHEMBL9060928 | 0.68 | ATM (0.39) | ALDH1A1MAPTL3MBTL1NPSR1LMNA | |
| SCHEMBL9059608 | 0.68 | CYP2A13 (0.52) | KMT2AMEN1ALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL9059565 | 0.67 | LGMN (0.46) | ALDH1A1MAPTL3MBTL1NPSR1NOTUM | |
| SCHEMBL9060134 | 0.65 | ALDH1A1 (0.55) | ALDH1A1MAPTLMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |