Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | AGER | Q15109 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 6/20 | 0.38 |
| ▸ | UBE2M | P61081 | 3/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807728 | 0.91 | TP53 (0.42) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL8809049 | 0.91 | TP53 (0.42) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL29972806 | 0.91 | TP53 (0.42) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL8808146 | 0.90 | TP53 (0.43) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL8817855 | 0.88 | ALDH1A1 (0.44) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL8808548 | 0.87 | TP53 (0.41) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL9058046 | 0.86 | UBE2M (0.41) | ALDH1A1KMT2AMEN1AGERHTR2A | |
| SCHEMBL8807796 | 0.84 | THRB (0.39) | TP53ALDH1A1KMT2AMEN1PPARG | |
| SCHEMBL8808860 | 0.83 | USP2 (0.43) | TP53ALDH1A1KMT2AUBE2MDCUN1D1 | |
| SCHEMBL9057934 | 0.83 | TP53 (0.41) | TP53HTR2AUBE2MDCUN1D1ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |