Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 11/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807728 | 0.92 | TP53 (0.42) | TP53HTR2ASCN9AABCB11CYP1A2 | |
| SCHEMBL8809049 | 0.92 | TP53 (0.42) | TP53HTR2ASCN9AABCB11CYP1A2 | |
| SCHEMBL29972806 | 0.92 | TP53 (0.42) | TP53HTR2ASCN9AABCB11CYP1A2 | |
| SCHEMBL8807796 | 0.85 | THRB (0.39) | TP53CYP1A2CYP2C19UBE2MDCUN1D1 | |
| SCHEMBL8808860 | 0.84 | USP2 (0.43) | TP53CYP1A2CYP2C19UBE2MDCUN1D1 | |
| SCHEMBL9056629 | 0.83 | KMT2A (0.38) | TP53CYP1A2CYP2C19UBE2MDCUN1D1 | |
| SCHEMBL9058046 | 0.83 | UBE2M (0.41) | HTR2ACYP1A2CYP2C19UBE2MDCUN1D1 | |
| SCHEMBL8808573 | 0.83 | LPAR1 (0.41) | TP53CYP1A2CYP2C19 | |
| SCHEMBL9059535 | 0.83 | TP53 (0.41) | TP53HTR2AABCB11CYP1A2ADRB2 | |
| SCHEMBL8808548 | 0.83 | TP53 (0.41) | TP53HTR2AABCB11CYP1A2ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |