Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059115 | 0.81 | KEAP1 (0.55) | ADRB1CD44ALDH1A1NPSR1MAPT | |
| SCHEMBL3436360 | 0.81 | ADRB1 (0.60) | LGMNADRB1ALDH1A1TSHRHTR7 | |
| SCHEMBL3555024 | 0.80 | ADRA2C (0.59) | ALDH1A1MAPTL3MBTL1MAPK1ADRA2C | |
| SCHEMBL9059418 | 0.79 | PRKDC (0.49) | LGMNADRB1ALDH1A1NPSR1MAPT | |
| SCHEMBL31321222 | 0.76 | ALDH1A1 (0.41) | ADRB1CD44ALDH1A1NPSR1MAPT | |
| SCHEMBL27195995 | 0.76 | ALDH1A1 (0.41) | ADRB1CD44ALDH1A1NPSR1MAPT | |
| SCHEMBL9060134 | 0.73 | ALDH1A1 (0.55) | ADRB1ALDH1A1MAPTTSHRMAPK1 | |
| SCHEMBL9424080 | 0.73 | KEAP1 (0.64) | LGMNALDH1A1MAPTL3MBTL1MAPK1 | |
| SCHEMBL4764212 | 0.71 | ADRB1 (0.42) | LGMNADRB1ALDH1A1NPSR1MAPT | |
| SCHEMBL29039627 | 0.71 | MAPT (0.69) | LGMNALDH1A1MAPTMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996017612-A1 | USE OF SUBSTITUTED PHENYLAMIDINE AND PHENYLGUANIDINE COMPOUNDS FOR THE TREATMENT OF CEREBRAL AND CARDIAC ISCHAEMIA, CONVULSION AND SICKLE CELL ANAEMIA | KNOLL AKTIENGESELLSCHAFT (DE) | 1996-06-13 | — | — | WO | disclosed |