Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 15/20 | 0.58 |
| ▸ | NOS3 | P29474 | 14/20 | 0.58 |
| ▸ | NOS2 | P35228 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12553926 | 0.91 | NOS1 (0.50) | NOS1NOS3NOS2POLBHTR3E | |
| SCHEMBL11311039 | 0.88 | NOS3 (0.65) | NOS1NOS3NOS2 | |
| SCHEMBL15561449 | 0.86 | NOS1 (0.70) | NOS1NOS3NOS2POLBSLC22A2 | |
| SCHEMBL486925 | 0.84 | NOS1 (0.67) | NOS1NOS3NOS2HTR3ESLC22A2 | |
| SCHEMBL16079475 | 0.84 | ADRA2A (0.60) | NOS1NOS3NOS2SLC22A2PLAU | |
| SCHEMBL15496398 | 0.82 | PLAU (0.65) | NOS1NOS3NOS2PLAU | |
| SCHEMBL12553935 | 0.82 | SLC22A2 (0.48) | NOS1NOS3NOS2POLBHTR3E | |
| SCHEMBL5112456 | 0.82 | NOS3 (0.72) | NOS1NOS3NOS2HTR3EHTR3B | |
| SCHEMBL15435836 | 0.82 | NOS1 (0.72) | NOS1NOS3NOS2 | |
| SCHEMBL12553932 | 0.80 | HTR3E (0.50) | NOS1NOS3NOS2POLBHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530063-A | HIGH-STRENGTH ADHESIVE COMPRISING A POLYSILOXANE HAVING END-GROUPS, AN ADDITION POLYMER, AN EPOXY COMPOUND, A CURING AGENT AND A CURING CATALYST | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0374269-A1 | Amine thiocyanates as accelerators for cure of polyepoxide-polyimine materials | Ashland Oil, Inc. (US) | 1990-06-27 | — | — | EP | disclosed |