Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 14/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 14/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9062240 | 0.91 | HCRTR1 (0.41) | HCRTR1HCRTR2L3MBTL1TSHRDAO | |
| SCHEMBL9060258 | 0.91 | ALOX5 (0.39) | HCRTR1HCRTR2L3MBTL1TSHRDAO | |
| SCHEMBL9061450 | 0.89 | ALOX5 (0.38) | HCRTR1HCRTR2TSHRDAOFFAR4 | |
| SCHEMBL9061433 | 0.85 | DAO (0.46) | TSHRDAOFFAR4 | |
| SCHEMBL9061734 | 0.85 | TSHR (0.43) | TSHRDAOFFAR4 | |
| SCHEMBL10532774 | 0.85 | PPARG (0.39) | HCRTR1HCRTR2DAOFFAR4 | |
| SCHEMBL20346149 | 0.85 | FFAR4 (0.43) | L3MBTL1FFAR4 | |
| SCHEMBL9060747 | 0.83 | TSHR (0.41) | TSHRDAO | |
| SCHEMBL14362913 | 0.83 | FFAR4 (0.41) | HCRTR1HCRTR2L3MBTL1FFAR4 | |
| SCHEMBL20346147 | 0.82 | GABRA1 (0.40) | FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5536442-A | ELECTROOPTICS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1996-07-16 | — | — | US | disclosed |
| US-5324449-A | Substituted phenyl trifluoromethyl ethers | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-06-28 | — | — | US | disclosed |
| EP-0334911-B1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK PATENT GmbH (DE) | 1993-02-10 | — | — | EP | disclosed |
| EP-0334911-A1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK PATENT GmbH (DE) | 1989-10-04 | — | — | EP | disclosed |
| WO-1989002884-A1 | SUBSTITUTED PHENYLTRIFLUORMETHYLETHERS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1989-04-06 | — | — | WO | disclosed |