SCHEMBL9060573

SCHEMBL9060573

CCCCCCCC(=O)c1ccc(-c2ccc(Br)cc2F)cc1

nearest known ligand 0.54

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RARB P10826 1/20 0.54
HSD17B3 P37058 7/20 0.51
HDAC1 Q13547 2/20 0.49
HDAC8 Q9BY41 2/20 0.49
HTR7 P34969 1/20 0.49
RORC P51449 2/20 0.48
RORA P35398 1/20 0.48
NR1H4 Q96RI1 1/20 0.48
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
STS P08842 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694999 0.95 HTR7 (0.55) RARBHSD17B3HDAC1HDAC8HTR7
SCHEMBL13670550 0.90 HDAC1 (0.51) RARBHDAC1HDAC8HTR7RORC
SCHEMBL8995506 0.84 MAPT (0.47) RARB
SCHEMBL7862901 0.81 FFAR1 (0.51) RARBHDAC1HDAC8
SCHEMBL7789360 0.80 HSD17B3 (0.71) HSD17B3HDAC1HDAC8HTR7THRA
SCHEMBL4293741 0.80 HSD17B3 (0.71) HSD17B3HDAC1HDAC8HTR7THRA
SCHEMBL7788804 0.80 HSD17B3 (0.71) HSD17B3HDAC1HDAC8HTR7THRA
SCHEMBL7789291 0.80 HSD17B3 (0.71) HSD17B3HDAC1HDAC8HTR7THRA
SCHEMBL7907717 0.80 HSD17B3 (0.71) HSD17B3HDAC1HDAC8HTR7THRA
SCHEMBL9493759 0.79 HTR7 (0.55) RARBHSD17B3HDAC1HDAC8HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5494605-A FERROELECTRIC, CHEMICALLY STABLE WITH WIDE TEMPERATURE RANGE KANTO KAGAKU KABUSHIKI KAISHA (JP) 1996-02-27 US disclosed
US-5382380-A Ferroelectric material for displays KANTO KAGAKU KABUSHIKI KAISHA (JP) 1995-01-17 US disclosed
EP-0414230-B1 Liquid crystal composition and liquid crystal device containing the same SHARP KK (JP) 1995-01-04 EP disclosed
EP-0360043-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1994-11-09 EP disclosed
US-5271867-A Liquid crystal composition and liquid crystal device containing the same SHARP KABUSHIKI KAISHA (JP) 1993-12-21 US disclosed
EP-0360042-B1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU (JP) 1993-11-03 EP disclosed
EP-0414230-A2 Liquid crystal composition and liquid crystal device containing the same SHARP KABUSHIKI KAISHA (JP) 1991-02-27 EP disclosed
EP-0360043-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed
EP-0360042-A1 p-Terphenyl derivatives and liquid crystalline compositions KANTO KAGAKU KABUSHIKI KAISHA (JP) 1990-03-28 EP disclosed