Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10694999 | 0.86 | HTR7 (0.55) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL9060573 | 0.84 | RARB (0.54) | RARB | |
| SCHEMBL5549813 | 0.83 | MMP1 (0.49) | MAPTSMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL7862901 | 0.82 | FFAR1 (0.51) | L3MBTL1SMN1; SMN2MMP1MMP2MMP3 | |
| SCHEMBL8218301 | 0.81 | MMP2 (0.50) | MMP1MMP2MMP3MMP7MMP9 | |
| SCHEMBL13670550 | 0.80 | HDAC1 (0.51) | MAPTL3MBTL1MMP1MMP2MMP3 | |
| SCHEMBL8207287 | 0.80 | MMP1 (0.49) | MAPTL3MBTL1SMN1; SMN2MMP1MMP2 | |
| SCHEMBL8208555 | 0.80 | DGAT1 (0.54) | MAPTL3MBTL1MMP1MMP2MMP3 | |
| SCHEMBL10916811 | 0.79 | CYP2C19 (0.51) | MAPTL3MBTL1SMN1; SMN2RARBALDH1A1 | |
| SCHEMBL10924018 | 0.79 | RARB (0.55) | MAPTL3MBTL1SMN1; SMN2RARBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0535635-B1 | Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition | SEIKO EPSON CORP (JP) | 1996-08-21 | — | — | EP | disclosed |
| US-5437815-A | Blending with ordinary liquid crystal compounds broadens practical temperature range of composition and produces an enlarged double refraction anisotropy | SEIKO EPSON CORPORATION (JP) | 1995-08-01 | — | — | US | disclosed |