SCHEMBL9060654

SCHEMBL9060654

CCc1ccc(NC(=O)c2ccc(C(=O)O)cn2)cc1CC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 1/20 0.54
LMNA P02545 1/20 0.54
KMT2A Q03164 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
P4HTM Q9NXG6 16/20 0.53
KDM4E B2RXH2 1/20 0.51
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
POLB P06746 1/20 0.51
P4HA1 P13674 1/20 0.49
MIF P14174 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8459282 0.83 KMT2A (0.54) ALDH1A1MEN1KMT2ANPC1RAB9A
SCHEMBL13210717 0.79 ALDH1A1 (0.65) ALDH1A1P4HTMKDM4ENPC1RAB9A
SCHEMBL8556508 0.77 P4HTM (0.51) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL6450288 0.76 ALDH1A1 (0.84) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL24892307 0.76 P4HTM (0.62) ALDH1A1MEN1KMT2AP4HTMKDM4E
SCHEMBL30182387 0.76 P4HTM (0.62) ALDH1A1MEN1KMT2AP4HTMKDM4E
SCHEMBL9207859 0.75 PKM (0.57) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL1458011 0.75 MEN1 (0.60) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL9121207 0.74 P4HTM (0.50) ALDH1A1MEN1LMNAKMT2ASMN1; SMN2
SCHEMBL8557337 0.74 RARB (0.73) ALDH1A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-8301760-A None JP disclosed
JP-H08301760-A SKIN PREPARATION FOR EXTERNAL USE SHISEIDO CO LTD 1996-11-19 JP disclosed