Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 7/20 | 0.40 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768148 | 0.78 | TDP1 (0.50) | ALDH1A1HSD17B10KDM4EKMT2ACYP2C9 | |
| SCHEMBL7929087 | 0.76 | CYP2D6 (0.55) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL2710225 | 0.76 | CYP2D6 (0.55) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL8732737 | 0.76 | CYP2D6 (0.55) | ALDH1A1KDM4EKMT2AMEN1MAPT | |
| SCHEMBL11267446 | 0.74 | TDP1 (0.42) | ALDH1A1HSD17B10KMT2ACYP2C9MEN1 | |
| SCHEMBL8611247 | 0.73 | CYP19A1 (0.51) | ALDH1A1CYP1A2 | |
| SCHEMBL7032426 | 0.73 | CYP19A1 (0.51) | ALDH1A1CYP1A2 | |
| SCHEMBL4620169 | 0.73 | GAA (0.51) | ALDH1A1KMT2AMAPT | |
| SCHEMBL7598667 | 0.73 | ELANE (0.57) | ALDH1A1KMT2ALMNA | |
| SCHEMBL7015768 | 0.73 | MAOA (0.46) | ALDH1A1KDM4EKMT2ACYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996035417-A1 | COMBINATIONS OF ANTI-OESTROGEN COMPOUNDS AND PKC MODULATORS AND THEIR USE IN CANCER THERAPY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1996-11-14 | — | — | WO | disclosed |